Intracellular calcium as an index of neurotoxic damage
نویسندگان
چکیده
منابع مشابه
assessment of the park- ang damage index for performance levels of rc moment resisting frames
چکیده هدف اصلی از طراحی لرزه ای تامین ایمنی جانی در هنگام وقوع زلزله و تعمیر پذیر بودن سازه خسارت دیده، پس از وقوع زلزله است. تجربه زلزله های اخیر نشان داده است که ساختمان های طراحی شده با آیین نامه های مبتنی بر نیرو از نظر محدود نمودن خسارت وارده بر سازه دقت لازم را ندارند. این امر سبب پیدایش نسل جدید آیین نامه های مبتنی بر عملکرد شده است. در این آیین نامه ها بر اساس تغییرشکل های غیرارتجاعی ...
15 صفحه اولNAADP as an intracellular messenger regulating lysosomal calcium-release channels.
Recent studies into the mechanisms of action of the Ca(2+)-mobilizing messenger NAADP (nicotinic acid-adenine dinucleotide phosphate) have demonstrated that a novel family of intracellular Ca(2+)-release channels termed TPCs (two-pore channels) are components of the NAADP receptor. TPCs appear to be exclusively localized to the endolysosomal system. These findings confirm previous pharmacologic...
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The calcium-regulated photoproteins, of which aequorin is the best known, continue to be one of the most useful groups of intracellular Ca2+ indicators. They are self-contained bioluminescent systems that emit blue light in the presence of Ca2+ ions, can readily be purified intact, and are nontoxic when introduced into foreign cells. They have been used successfully as Ca2+ indicators in almost...
متن کاملThe group of calcium-binding proteins known as the cal- bindins (CaBPs) plays a cardinal role in calcium metabo- lism, acting either as an intracellular facilitator of calcium diffusion or as an intracellular buffer of calcium (Wasser-
The group of calcium-binding proteins known as the calbindins (CaBPs) plays a cardinal role in calcium metabolism, acting either as an intracellular facilitator of calcium diffusion or as an intracellular buffer of calcium (Wasserman and Fullmer, 1983; Norman, 1990). The presence of CaBP-D28K in nerve terminals (Jande et al., 1981a,b; Baimbridge and Miller, 1982; Resibois et al., 1988a) suggest...
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ژورنال
عنوان ژورنال: Toxicology
سال: 1988
ISSN: 0300-483X
DOI: 10.1016/0300-483x(88)90171-0